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Mare/Nprl3/C16orf35 antibody (AA 349-482)

C16orf35 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7153701
  • Target See all Mare/Nprl3/C16orf35 (C16orf35) Antibodies
    Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
    Binding Specificity
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 349-482
    Reactivity
    • 10
    • 1
    Human
    Host
    • 5
    • 4
    • 1
    Rabbit
    Clonality
    • 7
    • 3
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    This Mare/Nprl3/C16orf35 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human GATOR complex protein NPRL3 protein (349-482AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
    Alternative Name
    NPRL3 (C16orf35 Products)
    Synonyms
    C16orf35 antibody, CGTHBA antibody, HS-40 antibody, MARE antibody, NPR3 antibody, RMD11 antibody, Aag antibody, HS-26 antibody, Mare antibody, Phg antibody, Prox1 antibody, m(alpha)RE antibody, RGD1308665 antibody, c16orf35 antibody, cgthba antibody, hs-40 antibody, mare antibody, npr3 antibody, nprl3 antibody, rmd11 antibody, NPR3 like, GATOR1 complex subunit antibody, nitrogen permease regulator-like 3 antibody, NPR3-like, GATOR1 complex subunit antibody, NPR3-like, GATOR1 complex subunit L homeolog antibody, NPRL3 antibody, Nprl3 antibody, nprl3.L antibody
    Background

    Background: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

    Aliases: otein antibody, Alpha-globin regulatory element-containing gene protein antibody, C16ORF35 antibody, CGTHBA antibody, Conserved gene telomeric to alpha globin cluster antibody, HS 40 antibody, MARE antibody, Nitrogen permease regulator 3-like protein antibody, Nitrogen permease regulator-like 3 (S. cerevisiae) antibody, NPR3 antibody, NPRL3 antibody, NPRL3_HUMAN antibody, Protein CGTHBA antibody, RMD11 antibody

    UniProt
    Q12980
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