Glutamate Receptor 1 antibody (AA 19-300)

Catalog No. ABIN7153960

The Rabbit Polyclonal anti-Glutamate Receptor 1 antibody (ABIN7153960) specifically detects Glutamate Receptor 1 in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for Glutamate Receptor 1 antibody (AA 19-300) (ABIN7153960)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: AA 19-300

Purpose: GRIA1 Antibody

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Glutamate receptor 1 protein (19-300AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GRIA1

Background:

Background: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Aliases: GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, OTTHUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody

UniProt: P42261

Pathways: PI3K-Akt Signaling