QPCT antibody (AA 29-361)

Catalog No. ABIN7154027

Product Details anti-QPCT Antibody

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Binding Specificity: AA 29-361

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QPCT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glutaminyl-peptide cyclotransferase protein (29-361AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for QPCT

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Alternative Name: QPCT (QPCT Products)

Synonyms: GCT antibody, QC antibody, sQC antibody, QPCT antibody, 5730422A13Rik antibody, Qpctl1 antibody, RGD1562284 antibody, qpct antibody, glutaminyl-peptide cyclotransferase antibody, glutaminyl-peptide cyclotransferase (glutaminyl cyclase) antibody, glutaminyl-peptide cyclotransferase L homeolog antibody, QPCT antibody, Qpct antibody, M6_Spy0443 antibody, M5005_Spy_0416 antibody, M28_Spy0404 antibody, CJA_2408 antibody, CCNA_02733 antibody, Tsp_03182 antibody, qpct.L antibody

Background:

Background: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Aliases: 5730422A13Rik antibody, EC antibody, GCT antibody, Glutaminyl cyclase antibody, Glutaminyl peptide cyclotransferase antibody, Glutaminyl tRNA cyclotransferase antibody, Glutaminyl-peptide cyclotransferase antibody, Glutaminyl-tRNA cyclotransferase antibody, Glutamyl cyclase antibody, QC antibody, qpct antibody, QPCT_HUMAN antibody, sQC antibody

UniProt: Q16769