GAPDH antibody (AA 2-335) (FITC)

Catalog No. ABIN7154136

The Rabbit Polyclonal anti-GAPDH antibody has been validated for . It is suitable to detect GAPDH in samples from Human.

Quick Overview for GAPDH antibody (AA 2-335) (FITC) (ABIN7154136)

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAPDH antibody is conjugated to FITC

Application: Please inquire

Product Details anti-GAPDH Antibody (FITC)

Binding Specificity: AA 2-335

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase protein (2-335AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GAPDH

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Alternative Name: GAPDH

Background:

Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Aliases: 38 kDa BFA-dependent ADP-ribosylation substrate antibody, aging associated gene 9 protein antibody, Aging-associated gene 9 protein antibody, BARS-38 antibody, cb609 antibody, EC 1.2.1.12 antibody, Epididymis secretory sperm binding protein Li 162eP antibody, G3P_HUMAN antibody, G3PD antibody, G3PDH antibody, GAPD antibody, GAPDH antibody, Glyceraldehyde 3 phosphate dehydrogenase antibody, glyceraldehyde 3-PDH antibody, Glyceraldehyde-3-phosphate dehydrogenase antibody, HEL-S-162eP antibody, KNC-NDS6 antibody, MGC102544 antibody, MGC102546 antibody, MGC103190 antibody, MGC103191 antibody, MGC105239 antibody, MGC127711 antibody, MGC88685 antibody, OCAS, p38 component antibody, OCT1 coactivator in S phase, 38-KD component antibody, peptidyl cysteine S nitrosylase GAPDH antibody, Peptidyl-cysteine S-nitrosylase GAPDH antibody, wu:fb33a10 antibody

UniProt: P04406