HLTF antibody (AA 332-476)

Catalog No. ABIN7154943

The Rabbit Polyclonal anti-HLTF antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect HLTF in samples from Human.

Quick Overview for HLTF antibody (AA 332-476) (ABIN7154943)

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLTF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-HLTF Antibody

Binding Specificity: AA 332-476

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Helicase-like transcription factor protein (332-476AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HLTF

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Alternative Name: HLTF

Background:

Background: Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for \\\'Lys-63\\\'-linked polyubiquitination of chromatin-bound PCNA.

Aliases: DNA-binding protein/plasminogen activator inhibitor 1 regulator antibody, Helicase like transcription factor antibody, Helicase-like transcription factor antibody, HIP116 antibody, HIP116A antibody, HLTF 1 antibody, Hltf antibody, HLTF_HUMAN antibody, HLTF1 antibody, p113 antibody, RING finger protein 80 antibody, RNF80 antibody, SMARC A3 antibody, SMARCA 3 antibody, SMARCA3 antibody, SNF2-like 3 antibody, SNF2L3 antibody, Sucrose nonfermenting protein 2 like 3 antibody, Sucrose nonfermenting protein 2-like 3 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 antibody, ZBU 1 antibody, ZBU1 antibody

UniProt: Q14527