Fc epsilon RI/FCER1A antibody (AA 26-205)

Catalog No. ABIN7155180

Product Details anti-Fc epsilon RI/FCER1A Antibody

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Binding Specificity: AA 26-205

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fc epsilon RI/FCER1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human High affinity immunoglobulin epsilon receptor subunit alpha protein (26-205AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Fc epsilon RI/FCER1A

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Alternative Name: FCER1A (FCER1A Products)

Synonyms: FCER1A antibody, FCE1A antibody, FcERI antibody, Iger01 antibody, RATIGER01 antibody, Fce1a antibody, Fcr-5 antibody, fcepsilonri antibody, Fc fragment of IgE receptor Ia antibody, Fc receptor, IgE, high affinity I, alpha polypeptide antibody, FCER1A antibody, Fcer1a antibody

Background:

Background: Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.

Aliases: Fc epsilon RI alpha antibody, Fc epsilon RI alpha chain antibody, Fc epsilon RI alpha-chain antibody, Fc fragment of IgE high affinity I receptor for alpha polypeptide antibody, Fc fragment of IgE, high affinity I, receptor for, alpha subunit antibody, Fc fragment of IgE, high affinity I, receptor for, alpha polypeptide antibody, Fc IgE receptor alpha polypeptide antibody, Fc IgE receptor, alpha chain antibody, Fc IgE receptor, alpha polypeptide antibody, Fc of IgE high affinity I receptor for alpha polypeptide antibody, Fc-epsilon RI-alpha antibody, FCE 1A antibody, FCE1A antibody, FCER 1A antibody, Fcer1a antibody, FCERA_HUMAN antibody, FceRI alpha antibody, FcERI antibody, high affinity IgE receptor antibody, High affinity immunoglobulin epsilon receptor alpha subunit antibody, high affinity immunoglobulin epsilon receptor alpha-subunit antibody, High affinity immunoglobulin epsilon receptor subunit alpha antibody, IgE Fc receptor alpha subunit antibody, IgE Fc receptor subunit alpha antibody, Immunoglobulin E receptor high affinity of mast cells alpha polypeptide antibody, immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide antibody

UniProt: P12319

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process