HMGB1 antibody (AA 8-179)

Catalog No. ABIN7155205

This anti-HMGB1 antibody is a Rabbit Polyclonal antibody detecting HMGB1 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for HMGB1 antibody (AA 8-179) (ABIN7155205)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-HMGB1 Antibody

Binding Specificity: AA 8-179

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human High mobility group protein B1 protein (8-179AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HMGB1

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Alternative Name: HMGB1

Background:

Background: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.

Aliases: Amphoterin antibody, Chromosomal protein, nonhistone, HMG1 antibody, DKFZp686A04236 antibody, High mobility group 1 antibody, High mobility group box 1 antibody, High mobility group protein 1 antibody, High mobility group protein B1 antibody, high-mobility group (nonhistone chromosomal) protein 1 antibody, HMG-1 antibody, HMG1 antibody, HMG3 antibody, HMGB 1 antibody, HMGB1 antibody, HMGB1_HUMAN antibody, NONHISTONE CHROMOSOMAL PROTEIN HMG1 antibody, SBP 1 antibody, Sulfoglucuronyl carbohydrate binding protein antibody

UniProt: P09429

Pathways: p53 Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome