H2AFV antibody (AA 1-128) (Biotin)

Catalog No. ABIN7155382

This anti-H2AFV antibody is a Rabbit Polyclonal antibody detecting H2AFV in ELISA. Suitable for Human.

Quick Overview for H2AFV antibody (AA 1-128) (Biotin) (ABIN7155382)

Target: H2AFV (H2A Histone Family, Member V (H2AFV))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFV antibody is conjugated to Biotin

Application: ELISA

Product Details anti-H2AFV Antibody (Biotin)

Binding Specificity: AA 1-128

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone H2A.V protein (1-128AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for H2AFV

Target: H2AFV (H2A Histone Family, Member V (H2AFV))

Alternative Name: H2AFV

Background:

Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Aliases: H2AFV antibody, H2AV antibody, Histone H2A.V antibody, H2A.F/Z antibody

UniProt: Q71UI9