DLX5 antibody (AA 1-249)

Catalog No. ABIN7155679

This anti-DLX5 antibody is a Rabbit Polyclonal antibody detecting DLX5 in ELISA, IHC and IF. Suitable for Human.

Quick Overview for DLX5 antibody (AA 1-249) (ABIN7155679)

Target: DLX5 (Distal-Less Homeobox 5 (DLX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLX5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DLX5 Antibody

Binding Specificity: AA 1-249

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Homeobox protein DLX-5 protein (1-249AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DLX5

Target: DLX5 (Distal-Less Homeobox 5 (DLX5))

Alternative Name: DLX5

Background:

Background: Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5\'-TAATTA-3\' consensus sequence for DNA-binding.

Aliases: DLX5Homeobox protein DLX-5 antibody

UniProt: P56178