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MEIS2 antibody (AA 377-470) (Biotin)

MEIS2 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7155787
  • Target See all MEIS2 Antibodies
    MEIS2 (Meis Homeobox 2 (MEIS2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 377-470
    Reactivity
    • 43
    • 17
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Human
    Host
    • 38
    • 5
    • 1
    Rabbit
    Clonality
    • 31
    • 13
    Polyclonal
    Conjugate
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MEIS2 antibody is conjugated to Biotin
    Application
    • 34
    • 21
    • 16
    • 13
    • 4
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Homeobox protein Meis2 protein (377-470AA)
    Isotype
    IgG
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    Discover our top product MEIS2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MEIS2 (Meis Homeobox 2 (MEIS2))
    Alternative Name
    MEIS2 (MEIS2 Products)
    Synonyms
    HsT18361 antibody, MRG1 antibody, A430109D20Rik antibody, Mrg1 antibody, Stra10 antibody, Meis2a.1 antibody, Meis2a.2 antibody, mrg1 antibody, MEIS2 antibody, hst18361 antibody, DKFZp469A1832 antibody, fa26d08 antibody, meis2.2 antibody, wu:fa26d08 antibody, meis2 antibody, meis2.1 antibody, Meis homeobox 2 antibody, Meis homeobox 2 L homeolog antibody, Meis homeobox 2a antibody, Meis homeobox 2b antibody, MEIS2 antibody, Meis2 antibody, meis2.L antibody, meis2 antibody, meis2a antibody, meis2b antibody
    Background

    Background: Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element, MEIS2 is not involved in complex DNA-binding. Probably in complex with PBX1, is involved in transcriptional regulation by KLF4. Isoform 3 and isoform 4 can bind to a EPHA8 promoter sequence containing the DNA motif 5\'-CGGTCA-3\', in cooperation with a PBX protein (such as PBX2) is proposed to be involved in the transcriptional activation of EPHA8 in the developing midbrain. May be involved in regulation of myeloid differentiation. Can bind to the DNA sequence 5\'-TGACAG-3\'in the activator ACT sequence of the D(1A) dopamine receptor (DRD1) promoter and activate DRD1 transcription, isoform 5 cannot activate DRD1 transcription.

    Aliases: Homeobox protein Meis2 antibody, HsT18361 antibody, Meis (mouse) homolog 2 antibody, Meis homeobox 2 antibody, Meis homolog 2 antibody, Meis1 myeloid ecotropic viral integration site 1 homolog 2 (mouse) antibody, Meis1 myeloid ecotropic viral integration site 1 homolog 2 antibody, Meis1 related gene 1 antibody, Meis1 related protein 1 antibody, Meis1-related protein 1 antibody, MEIS2 antibody, MEIS2_HUMAN antibody, MGC2820 antibody, MRG1 antibody, TALE homeobox protein Meis2 antibody

    UniProt
    O14770
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