FKBP6 antibody (AA 101-327) (Biotin)

Catalog No. ABIN7156156

Product Details anti-FKBP6 Antibody (Biotin)

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Binding Specificity: AA 101-327

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP6 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Inactive peptidyl-prolyl cis-trans isomerase FKBP6 protein (101-327AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FKBP6

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Alternative Name: FKBP6 (FKBP6 Products)

Synonyms: 1700008G22Rik antibody, 36kDa antibody, AU017274 antibody, D5Ertd724e antibody, FKBP-36 antibody, FKBP-6 antibody, PPiase antibody, FKBP36 antibody, FK506 binding protein 6 antibody, FK506 binding protein 6 L homeolog antibody, Fkbp6 antibody, fkbp6.L antibody, FKBP6 antibody

Background:

Background: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

Aliases: 36 kDa FK506 binding protein antibody, 36 kDa FK506-binding protein antibody, 36 kDa FKBP antibody, EC 5.2.1.8 antibody, FK506 binding protein 6 antibody, FK506-binding protein 6 antibody, FKBP 36 antibody, FKBP-36 antibody, FKBP-6 antibody, FKBP36 antibody, fkbp6 antibody, FKBP6_HUMAN antibody, Immunophilin FKBP36 antibody, Peptidyl prolyl cis trans isomerase antibody, Peptidyl-prolyl cis-trans isomerase FKBP6 antibody, PPIase antibody, PPIase FKBP6 antibody, Rotamase antibody

UniProt: O75344

Pathways: M Phase