ROR1 antibody (AA 30-391)

Catalog No. ABIN7156195

This anti-ROR1 antibody is a Rabbit Polyclonal antibody detecting ROR1 in ELISA and IHC. Suitable for Human.

Quick Overview for ROR1 antibody (AA 30-391) (ABIN7156195)

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROR1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ROR1 Antibody

Binding Specificity: AA 30-391

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Inactive tyrosine-protein kinase transmembrane receptor ROR1 protein (30-391AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:10-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ROR1

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Alternative Name: ROR1

Background:

Background: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed:27162350).

Aliases: dJ537F10.1 antibody, Inactive tyrosine protein kinase transmembrane receptor ROR1 antibody, MGC99659 antibody, Neurotrophic tyrosine kinase antibody, Neurotrophic tyrosine kinase receptor related 1 antibody, Neurotrophic tyrosine kinase, receptor related 1 antibody, NTRKR1 antibody, OTTHUMP00000010573 antibody, OTTHUMP00000010574 antibody, OTTMUSP00000008344 antibody, Receptor tyrosine kinase like orphan receptor 1 antibody, receptor-related 1 antibody, RGD1559469 antibody, ROR 1 antibody, ROR1 antibody, ROR1_HUMAN antibody, RP11 24J23.1 antibody, Tyrosine kinase like orphan receptor 1 antibody, Tyrosine protein kinase transmembrane receptor ROR1 antibody, Tyrosine-protein kinase transmembrane receptor ROR1 antibody

UniProt: Q01973

Pathways: RTK Signaling, WNT Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha