IRF2 antibody (AA 120-349)

Catalog No. ABIN7156617

The Rabbit Polyclonal anti-IRF2 antibody has been validated for ELISA and IHC. It is suitable to detect IRF2 in samples from Human.

Quick Overview for IRF2 antibody (AA 120-349) (ABIN7156617)

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-IRF2 Antibody

Binding Specificity: AA 120-349

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Interferon regulatory factor 2 protein (120-349AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Alternative Name: IRF2

Background:

Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.

Aliases: DKFZp686F0244 antibody, Interferon regulatory factor 2 antibody, IRF 2 antibody, IRF-2 antibody, IRF2 antibody, IRF2_HUMAN antibody

UniProt: P14316