IL1R1 antibody (AA 18-320)

Catalog No. ABIN7156745

Product Details anti-IL1R1 Antibody

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Binding Specificity: AA 18-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1R1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-1 receptor type 1 protein (18-320AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL1R1

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Alternative Name: IL1R1 (IL1R1 Products)

Background:

Background: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Aliases: Antigen CD121a antibody, CD121 antigen-like family member A antibody, CD121a antibody, CD121a antigen antibody, D2S1473 antibody, IL 1 antibody, IL 1R 1 antibody, IL 1R alpha antibody, IL 1RT1 antibody, IL-1R-1 antibody, IL-1R-alpha antibody, IL-1RT-1 antibody, IL-1RT1 antibody, IL1 inhibitor antibody, IL1 Receptor I antibody, IL1R antibody, IL1R1 antibody, IL1R1_HUMAN antibody, IL1RA antibody, IL1RN antibody, IL1RT1 antibody, Interleukin 1 receptor alpha type 1 antibody, Interleukin 1 receptor antagonist protein (IRAP) antibody, Interleukin 1 receptor type I antibody, Interleukin receptor 1 antibody, Interleukin-1 receptor alpha antibody, Interleukin-1 receptor type 1 antibody, Interleukin-1 receptor type I antibody, p80 antibody

UniProt: P14778

Pathways: NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints