IL12RB1 antibody (AA 119-280) (Biotin)

Catalog No. ABIN7156774

This anti-IL12RB1 antibody is a Rabbit Polyclonal antibody detecting IL12RB1 in ELISA. Suitable for Human.

Quick Overview for IL12RB1 antibody (AA 119-280) (Biotin) (ABIN7156774)

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL12RB1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-IL12RB1 Antibody (Biotin)

Binding Specificity: AA 119-280

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-12 receptor subunit beta-1 protein (119-280AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL12RB1

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Alternative Name: IL12RB1

Background:

Background: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Aliases: CD212 antibody, cluster of differentiation 212 antibody, I12R1_HUMAN antibody, IL-12 receptor beta component antibody, IL-12 receptor subunit beta-1 antibody, IL-12R subunit beta-1 antibody, IL-12R-beta-1 antibody, IL-12RB1 antibody, IL12 receptor beta component antibody, IL12RB antibody, Il12rb1 antibody, IMD3 antibody, IMD30 antibody, Interleukin 12 receptor beta 1 chain antibody, Interleukin 12 receptor subunit beta 1 antibody, Interleukin-12 receptor subunit beta-1 antibody, MGC34454 antibody

UniProt: P42701

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation