IL-18 antibody (AA 1-193)
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- Target See all IL-18 (IL18) Antibodies
- IL-18 (IL18) (Interleukin 18 (IL18))
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Binding Specificity
- AA 1-193
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL-18 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Interleukin-18 protein (1-193AA)
- Isotype
- IgG
- Top Product
- Discover our top product IL18 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- IL-18 (IL18) (Interleukin 18 (IL18))
- Alternative Name
- IL18 (IL18 Products)
- Synonyms
- Igif antibody, Il-18 antibody, IL-18 antibody, IGIF antibody, ChIL-18 antibody, IL-1g antibody, IL1F4 antibody, IL18 antibody, interleukin 18 antibody, Il18 antibody, IL18 antibody
- Background
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Background: A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532). Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed:10653850).
Aliases: Iboctadekin antibody, IFN gamma inducing factor antibody, IFN-gamma-inducing factor antibody, IGIF antibody, IL 1 gamma antibody, IL 18 antibody, IL 1g antibody, IL-1 gamma antibody, IL-18 antibody, IL1 gamma antibody, IL18 antibody, IL18 protein antibody, IL18_HUMAN antibody, IL1F4 antibody, IL1g antibody, IL1gamma antibody, ILIF4 antibody, Interferon gamma inducing factor antibody, Interferon gamma-inducing factor antibody, Interleukin 1 gamma antibody, Interleukin 18 (interferon-gamma-inducing factor) antibody, Interleukin 18 antibody, Interleukin-1 gamma antibody, Interleukin-18 antibody, Interleukin18 antibody, MGC12320 antibody
- UniProt
- Q14116
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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