IREB2 antibody (AA 107-216) (HRP)

Catalog No. ABIN7157049

The Rabbit Polyclonal anti-IREB2 antibody has been validated for ELISA. It is suitable to detect IREB2 in samples from Human.

Quick Overview for IREB2 antibody (AA 107-216) (HRP) (ABIN7157049)

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IREB2 antibody is conjugated to HRP

Application: ELISA

Product Details anti-IREB2 Antibody (HRP)

Binding Specificity: AA 107-216

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Iron-responsive element-binding protein 2 protein (107-216AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IREB2

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Alternative Name: IREB2

Background:

Background: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5\'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3\'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Aliases: ACO3 antibody, FLJ23381 antibody, IRE BP2 antibody, IRE-BP 2 antibody, IREB 2 antibody, IREB2 antibody, IREB2_HUMAN antibody, Iron regulatory protein 2 antibody, iron responsive element binding protein 2 antibody, Iron-responsive element-binding protein 2 antibody, IRP 2 antibody, IRP2 antibody, IRP2AD antibody, OTTHUMP00000185022 antibody

UniProt: P48200

Pathways: Transition Metal Ion Homeostasis