JMJD5 antibody (AA 151-380)

Catalog No. ABIN7157150

This Rabbit Polyclonal antibody specifically detects JMJD5 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for JMJD5 antibody (AA 151-380) (ABIN7157150)

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-JMJD5 Antibody

Binding Specificity: AA 151-380

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human JmjC domain-containing protein 5 protein (151-380AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for JMJD5

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Alternative Name: KDM8

Background:

Background: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated \\\'Lys-36\\\' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

Aliases: FLJ13798 antibody, JmjC domain-containing protein 5 antibody, JMJD5 antibody, JMJD5 protein antibody, jumonji domain containing 5 antibody, Jumonji domain-containing protein 5 antibody, KDM8_HUMAN antibody, Lysine (K) specific demethylase 8 antibody, Lysine-specific demethylase 8 antibody

UniProt: Q8N371

Pathways: Chromatin Binding