SPC24 antibody (AA 21-97) (Biotin)

Catalog No. ABIN7157668

The Biotin-conjugated Rabbit Polyclonal anti-SPC24 antibody (ABIN7157668) specifically detects SPC24 in ELISA. The antibody is reactive with Human samples.

Quick Overview for SPC24 antibody (AA 21-97) (Biotin) (ABIN7157668)

Target: SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPC24 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-SPC24 Antibody (Biotin)

Binding Specificity: AA 21-97

Purpose: SPC24 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Kinetochore protein Spc24 protein (21-97AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SPC24

Target: SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))

Alternative Name: SPC24

Background:

Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).

Aliases: FLJ90806 antibody, hSpc24 antibody, Kinetochore protein Spc24 antibody, SPBC24 antibody, spc24 antibody, SPC24 NDC80 kinetochore complex component antibody, SPC24 NDC80 kinetochore complex component homolog antibody, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) antibody, SPC24_HUMAN antibody, Spindle pole body component 24 homolog (S. cerevisiae) antibody, Spindle pole body component 24 homolog antibody

UniProt: Q8NBT2