SPC24 antibody (AA 1-197)

Catalog No. ABIN7270514

Product Details anti-SPC24 Antibody

Target: SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))

Binding Specificity: AA 1-197

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPC24 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: SPC24 Rabbit pAb

Sequence: MAAFRDIEEV SQGLLSLLGA NRAEAQQRRL LGRHEQVVER LLETQDGAEK QLREILTMEK EVAQSLLNAK EQVHQGGVEL QQLEAGLQEA GEEDTRLKAS LLQLTRELEE LKEIEADLER QEKEVDEDTT VTIPSAVYVA QLYHQVSKIE WDYECEPGMV KGIHHGPSVA QPIHLDSTQL SRKFISDYLW SLVDTEW

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SPC24 (NP_872319.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPC24

Target: SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))

Alternative Name: SPC24 (SPC24 Products)

Synonyms: SPBC24 antibody, spbc24 antibody, 2410030K01Rik antibody, AV109292 antibody, Spbc24 antibody, wu:fb79a02 antibody, zgc:110417 antibody, SPC24, NDC80 kinetochore complex component antibody, SPC24, NDC80 kinetochore complex component L homeolog antibody, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) antibody, SPC24 antibody, spc24.L antibody, Spc24 antibody, spc24 antibody

Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.,SPC24,SPBC24,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centromere,SPC24

Molecular Weight: 17kDa/22kDa

Gene ID: 147841

UniProt: Q8NBT2