KIT Ligand antibody (AA 26-214)

Catalog No. ABIN7157685

The Rabbit Polyclonal anti-KIT Ligand antibody has been validated for WB and ELISA. It is suitable to detect KIT Ligand in samples from Human.

Quick Overview for KIT Ligand antibody (AA 26-214) (ABIN7157685)

Target: KIT Ligand (KITLG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIT Ligand antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KIT Ligand Antibody

Binding Specificity: AA 26-214

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Kit ligand protein (26-214AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KIT Ligand

Target: KIT Ligand (KITLG)

Alternative Name: KITLG

Background:

Background: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

Aliases: C kit ligand antibody, C-kit ligand antibody, Ckit ligand antibody, DCUA antibody, DFNA69 antibody, DKFZp686F2250 antibody, familial progressive hyperpigmentation 2 antibody, FPH2 antibody, FPHH antibody, KIT ligand antibody, Kitl antibody, KITLG antibody, KL 1 antibody, KL1 antibody, Mast cell growth factor antibody, MGF antibody, MGF stem cell factor antibody, SCF antibody, SCF_HUMAN antibody, SF antibody, SHEP7 antibody, sKITLG antibody, Soluble KIT ligand antibody, Steel factor antibody, steel, mouse, homolog of antibody, Stem cell factor antibody, Stem cell factor precursor antibody

UniProt: P21583

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway