KMO antibody (AA 1-260)

Catalog No. ABIN7157755

The Rabbit Polyclonal anti-KMO antibody (ABIN7157755) specifically detects KMO in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for KMO antibody (AA 1-260) (ABIN7157755)

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KMO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-KMO Antibody

Binding Specificity: AA 1-260

Purpose: KMO Antibody

Cross-Reactivity: Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Kynurenine 3-monooxygenase protein (1-260AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KMO

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Alternative Name: KMO

Background:

Background: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Aliases: dJ317G22.1 antibody, kmo antibody, KMO_HUMAN antibody, Kynurenine 3 hydroxylase antibody, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase) antibody, Kynurenine 3 monooxygenase antibody, Kynurenine 3-hydroxylase antibody, Kynurenine 3-monooxygenase antibody, RP1-317G22.1 antibody

UniProt: O15229