KMO antibody (AA 1-486)

Catalog No. ABIN7157756

This Rabbit Polyclonal antibody specifically detects KMO in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for KMO antibody (AA 1-486) (ABIN7157756)

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KMO antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-KMO Antibody

Binding Specificity: AA 1-486

Purpose: KMO Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Kynurenine 3-monooxygenase protein (1-486AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KMO

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Alternative Name: KMO

Background:

Background: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Aliases: dJ317G22.1 antibody, kmo antibody, KMO_HUMAN antibody, Kynurenine 3 hydroxylase antibody, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase) antibody, Kynurenine 3 monooxygenase antibody, Kynurenine 3-hydroxylase antibody, Kynurenine 3-monooxygenase antibody, RP1-317G22.1 antibody

UniProt: O15229