Mip (AA 220-263) antibody

Catalog No. ABIN7157984

Product Details

Target: Mip

Binding Specificity: AA 220-263

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lens fiber major intrinsic protein (220-263AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Mip

Synonyms: Aqp0 antibody, Cat antibody, Hfi antibody, Lop antibody, MIP26 antibody, Svl antibody, shrivelled antibody, major intrinsic protein of lens fiber antibody, Mip antibody

Background:

Background: Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (PubMed:24120416).

Aliases: AQP 0 antibody, AQP0 antibody, Aquaporin antibody, Aquaporin 0 antibody, Aquaporin-0 antibody, Aquaporin0 antibody, Lens fiber major intrinsic protein antibody, LIM 1 antibody, LIM1 antibody, Major intrinsic protein 26kD antibody, Major intrinsic protein of lens fiber antibody, MIP 26 antibody, mip antibody, MIP_HUMAN antibody, MIP26 antibody, MP 26 antibody, MP26 antibody, PALM antibody

UniProt: P30301