LINGO1 antibody (AA 42-240)

Catalog No. ABIN7158053

This Rabbit Polyclonal antibody specifically detects LINGO1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for LINGO1 antibody (AA 42-240) (ABIN7158053)

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-LINGO1 Antibody

Binding Specificity: AA 42-240

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 protein (42-240AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: LINGO1

Background:

Background: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Aliases: FLJ14594 antibody, LERN 1 antibody, LERN1 antibody, Leucine rich repeat and Ig domain containing 1 antibody, Leucine rich repeat neuronal 6A antibody, Leucine rich repeat neuronal protein 1 antibody, Leucine rich repeat neuronal protein 6A antibody, Leucine-rich repeat and immunoglobilin domain-containing protein 1 antibody, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 antibody, Leucine-rich repeat neuronal protein 1 antibody, Leucine-rich repeat neuronal protein 6A antibody, LIGO1_HUMAN antibody, Lingo 1 antibody, LINGO1 antibody, LRR and Ig domain containing Nogo Receptor interating protein antibody, Lrrn 6a antibody, Lrrn6a antibody, Lrrn6a protein antibody, MGC17422 antibody, Nogo Receptor interacting protein antibody, PRO227 antibody, UNQ201 antibody

UniProt: Q96FE5