FLRT3 antibody (AA 209-264) (Biotin)

Catalog No. ABIN7158123

Product Details anti-FLRT3 Antibody (Biotin)

Target: FLRT3 (Fibronectin Leucine Rich Transmembrane Protein 3 (FLRT3))

Binding Specificity: AA 209-264

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLRT3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Leucine-rich repeat transmembrane protein FLRT3 protein (209-264AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FLRT3

Target: FLRT3 (Fibronectin Leucine Rich Transmembrane Protein 3 (FLRT3))

Alternative Name: FLRT3 (FLRT3 Products)

Synonyms: flrt3 antibody, FLRT3 antibody, xflrt3 antibody, DKFZp459F141 antibody, 5530600M07Rik antibody, C430047I10Rik antibody, mKIAA1469 antibody, RGD1566005 antibody, HH21 antibody, fibronectin leucine rich transmembrane protein 3 S homeolog antibody, fibronectin leucine rich transmembrane protein 3 antibody, fibronectin leucine rich transmembrane protein 3 L homeolog antibody, flrt3.S antibody, FLRT3 antibody, flrt3.L antibody, flrt3 antibody, Flrt3 antibody

Background:

Background: Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity). Promotes neurite outgrowth (in vitro) (PubMed:14706654). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).

Aliases: fibronectin leucine rich transmembrane protein 3 antibody, Fibronectin-like domain-containing leucine-rich transmembrane protein 3 antibody, FLRT 3 antibody, FLRT3 antibody, FLRT3_HUMAN antibody, KIAA1469 antibody, Leucine-rich repeat transmembrane protein FLRT3 antibody

UniProt: Q9NZU0