LGR6 antibody (AA 839-962)

Catalog No. ABIN7158134

Product Details anti-LGR6 Antibody

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Binding Specificity: AA 839-962

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGR6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 6 protein (839-962AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LGR6

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Alternative Name: LGR6 (LGR6 Products)

Synonyms: LGR6 antibody, GPCR antibody, VTS20631 antibody, A530037C04Rik antibody, D830026M09 antibody, RGD1560339 antibody, leucine rich repeat containing G protein-coupled receptor 6 antibody, leucine-rich repeat-containing G protein-coupled receptor 6 antibody, LGR6 antibody, Lgr6 antibody

Background:

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

Aliases: FLJ14471 antibody, Gonadotropin receptor antibody, GPCR antibody, Leucine rich repeat containing G protein coupled receptor 6 antibody, Leucine-rich repeat-containing G-protein coupled receptor 6 antibody, Lgr6 antibody, LGR6_HUMAN antibody, VTS20631 antibody

UniProt: Q9HBX8