LGR6 antibody (AA 839-962) (HRP)

Catalog No. ABIN7158137

This Rabbit Polyclonal antibody specifically detects LGR6 in ELISA. It exhibits reactivity toward Human.

Quick Overview for LGR6 antibody (AA 839-962) (HRP) (ABIN7158137)

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGR6 antibody is conjugated to HRP

Application: ELISA

Product Details anti-LGR6 Antibody (HRP)

Binding Specificity: AA 839-962

Purpose: LGR6 Antibody, HRP conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 6 protein (839-962AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LGR6

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Alternative Name: LGR6

Background:

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

Aliases: FLJ14471 antibody, Gonadotropin receptor antibody, GPCR antibody, Leucine rich repeat containing G protein coupled receptor 6 antibody, Leucine-rich repeat-containing G-protein coupled receptor 6 antibody, Lgr6 antibody, LGR6_HUMAN antibody, VTS20631 antibody

UniProt: Q9HBX8