Leupaxin antibody (AA 1-300)

Catalog No. ABIN7158308

This Rabbit Polyclonal antibody specifically detects Leupaxin in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Leupaxin antibody (AA 1-300) (ABIN7158308)

Target: Leupaxin (LPXN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leupaxin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Leupaxin Antibody

Binding Specificity: AA 1-300

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Leupaxin protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Leupaxin

Target: Leupaxin (LPXN)

Alternative Name: LPXN

Background:

Background: Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling.

Aliases: LPXN antibody, LDLPLeupaxin antibody

UniProt: O60711