LONP1 antibody (AA 614-959)

Catalog No. ABIN7158488

Product Details anti-LONP1 Antibody

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Binding Specificity: AA 614-959

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LONP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lon protease homolog, mitochondrial protein (614-959AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Alternative Name: LONP1 (LONP1 Products)

Synonyms: PRSS15 antibody, prss15 antibody, fc64d11 antibody, wu:fc64d11 antibody, LON antibody, LONP antibody, LonHS antibody, PIM1 antibody, hLON antibody, 1200017E13Rik antibody, Prss15 antibody, Lon antibody, lon peptidase 1, mitochondrial antibody, ATP-dependent Lon protease antibody, LONP1 antibody, lonp1 antibody, Lonp1 antibody, PIM1 antibody

Background:

Background: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Aliases: hLON antibody, hLON ATP dependent protease antibody, LON antibody, lon peptidase 1, mitochondrial antibody, LON protease antibody, Lon protease homolog antibody, Lon protease like protein antibody, Lon protease-like protein antibody, LONHs antibody, LONM_HUMAN antibody, LONP antibody, Lonp1 antibody, MGC1498 antibody, mitochondrial antibody, Mitochondrial ATP dependent protease Lon antibody, Mitochondrial ATP-dependent protease Lon antibody, Mitochondrial lon peptidase 1 antibody, PIM1 antibody, Protease serine 15 antibody, PRSS15 antibody, Serine protease 15 antibody

UniProt: P36776