Kdm6b antibody (AA 1530-1682) (FITC)
Quick Overview for Kdm6b antibody (AA 1530-1682) (FITC) (ABIN7158722)
Target
See all Kdm6b AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1530-1682
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Lysine-specific demethylase 6B protein (1530-1682AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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Alternative Name
- KDM6B
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Background
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Background: Histone demethylase that specifically demethylates \'Lys-27\' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Demethylates trimethylated and dimethylated H3 \'Lys-27\' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402).
Aliases: Histone demethylase JMJD3 antibody, JmjC domain containing protein 3 antibody, JmjC domain-containing protein 3 antibody, Jumonji D3 antibody, Jumonji domain containing 3 antibody, Jumonji domain containing 3 histone lysine demethylase antibody, Jumonji domain containing protein 3 antibody, Jumonji domain-containing protein 3 antibody, Kdm6b antibody, KDM6B_HUMAN antibody, KIAA0346 antibody, Lysine demethylase 6B antibody, Lysine K specific demethylase 6B antibody, Lysine specific demethylase 6B antibody, Lysine-specific demethylase 6B antibody
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UniProt
- O15054
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Pathways
- Warburg Effect
Target
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