M-CSF/CSF1 antibody (AA 33-554) (Biotin)

Catalog No. ABIN7158867

The Rabbit Polyclonal anti-M-CSF/CSF1 antibody has been validated for ELISA. It is suitable to detect M-CSF/CSF1 in samples from Human.

Quick Overview for M-CSF/CSF1 antibody (AA 33-554) (Biotin) (ABIN7158867)

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This M-CSF/CSF1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-M-CSF/CSF1 Antibody (Biotin)

Binding Specificity: AA 33-554

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Macrophage colony-stimulating factor 1 protein (33-554AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Alternative Name: CSF1

Background:

Background: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

Aliases: Colony stimulating factor 1 (macrophage) antibody, Colony stimulating factor 1 antibody, Colony stimulating factor macrophage specific antibody, CSF 1 antibody, CSF-1 antibody, CSF1 antibody, CSF1_HUMAN antibody, Csfm antibody, Lanimostim antibody, M CSF antibody, M-CSF antibody, Macrophage Colony Stimulating Factor 1 antibody, Macrophage colony stimulating factor antibody, MCSF antibody, MGC31930 antibody, Processed macrophage colony-stimulating factor 1 antibody

UniProt: P09603

Pathways: RTK Signaling