MRGPRX2 antibody (AA 286-330) (HRP)

Catalog No. ABIN7159016

This Rabbit Polyclonal antibody specifically detects MRGPRX2 in ELISA. It exhibits reactivity toward Human.

Quick Overview for MRGPRX2 antibody (AA 286-330) (HRP) (ABIN7159016)

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGPRX2 antibody is conjugated to HRP

Application: ELISA

Product Details anti-MRGPRX2 Antibody (HRP)

Binding Specificity: AA 286-330

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Alternative Name: MRGPRX2

Background:

Background: Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.

Aliases: G protein coupled receptor MRGX 2 antibody, G protein coupled receptor MRGX2 antibody, Mas related G protein coupled receptor member X2 antibody, Mas related gene MRGX 2 antibody, Mas related gene MRGX2 antibody, MAS related GPR member X2 antibody, Mas-related G-protein coupled receptor member X antibody, Mas-related G-protein coupled receptor member X2 antibody, MRGPRX 2 antibody, MRGPRX2 antibody, MRGX 2 antibody, MRGX2 antibody, MRGX2_HUMAN antibody

UniProt: Q96LB1