MTBP antibody (AA 567-724)

Catalog No. ABIN7159086

The Rabbit Polyclonal anti-MTBP antibody has been validated for ELISA and IHC. It is suitable to detect MTBP in samples from Human.

Quick Overview for MTBP antibody (AA 567-724) (ABIN7159086)

Target: MTBP (MDM2 Binding Protein (MTBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTBP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-MTBP Antibody

Binding Specificity: AA 567-724

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mdm2-binding protein (567-724AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MTBP

Target: MTBP (MDM2 Binding Protein (MTBP))

Alternative Name: MTBP

Background:

Background: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.

Aliases: hMTBP antibody, MDM 2 binding protein antibody, MDM 2 BP antibody, MDM2 (mouse double minute 2) binding protein 104kD antibody, MDM2 (mouse double minute 2) binding protein antibody, MDM2 binding protein antibody, MDM2 BP antibody, Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104 kDa antibody, Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein antibody, Mdm2 transformed 3T3 cell double minute 2 p53 binding protein binding protein antibody, Mdm2-binding protein antibody, MDM2BP antibody, Mouse double minute 2 homolog binding protein antibody, MTBP antibody, MTBP_HUMAN antibody

UniProt: Q96DY7