MED28 antibody (AA 1-178) (HRP)

Catalog No. ABIN7159151

This Rabbit Polyclonal antibody specifically detects MED28 in ELISA. It exhibits reactivity toward Human.

Quick Overview for MED28 antibody (AA 1-178) (HRP) (ABIN7159151)

Target: MED28 (Mediator Complex Subunit 28 (MED28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED28 antibody is conjugated to HRP

Application: ELISA

Product Details anti-MED28 Antibody (HRP)

Binding Specificity: AA 1-178

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mediator of RNA polymerase II transcription subunit 28 protein (1-178AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MED28

Target: MED28 (Mediator Complex Subunit 28 (MED28))

Alternative Name: MED28

Background:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.

Aliases: EG1 antibody, Endothelial-derived protein 1 antibody, FKSG20 antibody, Magicin antibody, med28 antibody, MED28_HUMAN antibody, Mediator complex subunit 28 antibody, Mediator of RNA polymerase II transcription subunit 28 antibody, Merlin and Grb2-interacting cytoskeletal protein antibody, Tumor angiogenesis marker EG-1 antibody

UniProt: Q9H204

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation