MED4 antibody (AA 167-270)

Catalog No. ABIN7159160

This Rabbit Polyclonal antibody specifically detects MED4 in ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for MED4 antibody (AA 167-270) (ABIN7159160)

Target: MED4 (Mediator Complex Subunit 4 (MED4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-MED4 Antibody

Binding Specificity: AA 167-270

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mediator of RNA polymerase II transcription subunit 4 protein (167-270AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MED4

Target: MED4 (Mediator Complex Subunit 4 (MED4))

Alternative Name: MED4

Background:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Aliases: Activator-recruited cofactor 36 kDa component antibody, ARC36 antibody, DRIP36 antibody, FLJ10956 antibody, HSPC126 antibody, med4 antibody, MED4_HUMAN antibody, Mediator complex subunit 4 antibody, Mediator of RNA polymerase II transcription subunit 4 antibody, Mediator of RNA polymerase II transcription, subunit 4 homolog antibody, OTTHUMP00000018390 antibody, OTTHUMP00000018391 antibody, OTTHUMP00000018392 antibody, RP11-90M2.2 antibody, TRAP/SMCC/PC2 subunit p36 subunit antibody, TRAP36 antibody, VDRIP antibody, Vitamin D3 receptor-interacting protein complex 36 kDa component antibody

UniProt: Q9NPJ6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha