Majin (AA 1-216) antibody (HRP)
Quick Overview for Majin (AA 1-216) antibody (HRP) (ABIN7159351)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-216
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Purpose
- MAJIN Antibody, HRP conjugated
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Purification
- Protein G purified
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Purity
- >95 %
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Immunogen
- Recombinant Human Membrane-anchored junction protein (1-216AA)
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Isotype
- IgG
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anti-Majin (AA 1-216) antibody
Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Majin
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Background
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Background: Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane.
Aliases: MAJIN antibody, C11orf85Membrane-anchored junction protein antibody
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UniProt
- Q3KP22
Target
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