Meprin B antibody (AA 480-652)

Catalog No. ABIN7159412

This Rabbit Polyclonal antibody specifically detects Meprin B in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Meprin B antibody (AA 480-652) (ABIN7159412)

Target: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Meprin B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Meprin B Antibody

Binding Specificity: AA 480-652

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Meprin A subunit beta protein (480-652AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Meprin B

Target: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Alternative Name: MEP1B

Background:

Background: Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1\\\' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.

Aliases: Endopeptidase 2 antibody, Endopeptidase-2 antibody, kinase splitting membranal proteinase antibody, KSMP antibody, Mep1b antibody, MEP1B_HUMAN antibody, Meprin 1 beta subunit antibody, Meprin A beta antibody, Meprin A beta subunit precursor antibody, Meprin A subunit beta antibody, Meprin B antibody, N benzoyl L tyrosyl P amino benzoic acid hydrolase beta subunit antibody, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta antibody, PABA peptide hydrolase antibody, PPH beta antibody

UniProt: Q16820