MTRR antibody (AA 1-725)

Catalog No. ABIN7159589

This Rabbit Polyclonal antibody specifically detects MTRR in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for MTRR antibody (AA 1-725) (ABIN7159589)

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTRR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MTRR Antibody

Binding Specificity: AA 1-725

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Methionine synthase reductase protein (1-725AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MTRR

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Alternative Name: MTRR

Background:

Background: Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining the transgenerational epigenetic inheritance effects.

Aliases: MTRR antibody, Methionine synthase reductase antibody, MSR antibody, EC 1.16.1.8 antibody

UniProt: Q9UBK8

Pathways: Methionine Biosynthetic Process