APIP antibody (AA 1-242)

Catalog No. ABIN7159666

This anti-APIP antibody is a Rabbit Polyclonal antibody detecting APIP in WB, ELISA and IHC. Suitable for Human.

Quick Overview for APIP antibody (AA 1-242) (ABIN7159666)

Target: APIP (APAF1 Interacting Protein (APIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-APIP Antibody

Binding Specificity: AA 1-242

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Methylthioribulose-1-phosphate dehydratase protein (1-242AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APIP

Target: APIP (APAF1 Interacting Protein (APIP))

Alternative Name: APIP

Background:

Background: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Aliases: Apaf1 Interacting Protein antibody, APAF1-interacting protein antibody, APIP antibody, APIP2 antibody, CG129 antibody, CGI 29 antibody, CGI29 antibody, dJ179L10.2 antibody, MMRP19 antibody, Monocyte/macrophage protein 19 antibody, MTNB_HUMAN antibody, MTRu 1 P dehydratase antibody, MTRu-1-P dehydratase antibody, Probable methylthioribulose 1 phosphate dehydratase antibody, Probable methylthioribulose-1-phosphate dehydratase antibody

UniProt: Q96GX9

Pathways: Methionine Biosynthetic Process