LC3B antibody (AA 2-100) (Biotin)

Catalog No. ABIN7159783

This anti-LC3B antibody is a Rabbit Polyclonal antibody detecting LC3B in ELISA. Suitable for Human.

Quick Overview for LC3B antibody (AA 2-100) (Biotin) (ABIN7159783)

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LC3B antibody is conjugated to Biotin

Application: ELISA

Product Details anti-LC3B Antibody (Biotin)

Binding Specificity: AA 2-100

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Microtubule-associated proteins 1A/1B light chain 3B protein (2-100AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LC3B

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Alternative Name: MAP1LC3B

Background:

Background: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Aliases: ATG8F antibody, Autophagy-related protein LC3 B antibody, Autophagy-related ubiquitin-like modifier LC3 B antibody, LC3B antibody, LC3II antibody, MAP1 light chain 3 like protein 2 antibody, MAP1 light chain 3-like protein 2 antibody, MAP1A/1BLC3 antibody, MAP1A/MAP1B LC3 B antibody, MAP1A/MAP1B light chain 3 B antibody, MAP1ALC3 antibody, MAP1LC3B a antibody, Map1lc3b antibody, Microtubule associated protein 1 light chain 3 beta antibody, Microtubule-associated protein 1 light chain 3 beta antibody, Microtubule-associated proteins 1A/1B light chain 3B antibody, MLP3B_HUMAN antibody

UniProt: Q9GZQ8

Pathways: Autophagy