MCMBP antibody (AA 1-240)
Quick Overview for MCMBP antibody (AA 1-240) (ABIN7159821)
Target
See all MCMBP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-240
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Purpose
- MCMBP Antibody
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Mini-chromosome maintenance complex-binding protein (1-240AA)
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Isotype
- IgG
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anti-Minichromosome Maintenance Complex Binding Protein (MCMBP) antibody
MCMBP Reactivity: Human, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Binding Protein (MCMBP) (AA 1-240) antibodyMCMBP Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))
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Alternative Name
- MCMBP
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Background
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Background: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP, probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.
Aliases: MCMBP antibody, C10orf119 antibody, Mini-chromosome maintenance complex-binding protein antibody, MCM-BP antibody, MCM-binding protein antibody
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UniProt
- Q9BTE3
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Pathways
- Chromatin Binding
Target
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