CD14 antibody (AA 20-345)

Catalog No. ABIN7160181

The Rabbit Polyclonal anti-CD14 antibody has been validated for IHC, ELISA and IF. It is suitable to detect CD14 in samples from Human.

Quick Overview for CD14 antibody (AA 20-345) (ABIN7160181)

Target: CD14

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CD14 Antibody

Binding Specificity: AA 20-345

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Monocyte differentiation antigen CD14 protein (20-345AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background:

Background: Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135).

Aliases: CD 14 antibody, CD_antigen=CD14 antibody, CD14 antibody, CD14 antigen antibody, CD14 Molecule antibody, CD14_HUMAN antibody, LPS-R antibody, Mo2 antibody, Monocyte differentiation antigen CD14 antibody, Monocyte differentiation antigen CD14 urinary form antibody, Monocyte differentiation antigen CD14, membrane-bound form antibody, Myeloid cell specific leucine rich glycoprotein antibody, Myeloid cell-specific leucine-rich glycoprotein antibody

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades