SMAD1 antibody (AA 150-250) (HRP)

Catalog No. ABIN7160223

The Rabbit Polyclonal anti-SMAD1 antibody has been validated for ELISA. It is suitable to detect SMAD1 in samples from Human.

Quick Overview for SMAD1 antibody (AA 150-250) (HRP) (ABIN7160223)

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-SMAD1 Antibody (HRP)

Binding Specificity: AA 150-250

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mothers against decapentaplegic homolog 1 protein (150-250AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMAD1

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Alternative Name: SMAD1

Background:

Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Aliases: BSP-1 antibody, BSP1 antibody, HsMAD1 antibody, JV4-1 antibody, JV41 antibody, MAD homolog 1 antibody, MAD mothers against decapentaplegic homolog 1 antibody, Mad related protein 1 antibody, Mad-related protein 1 antibody, MADH1 antibody, MADR1 antibody, Mothers against decapentaplegic homolog 1 antibody, Mothers against DPP homolog 1 antibody, SMA- AND MAD-RELATED PROTEIN 1 antibody, SMAD 1 antibody, SMAD family member 1 antibody, SMAD mothers against DPP homolog 1 antibody, Smad1 antibody, SMAD1_HUMAN antibody, TGF beta signaling protein 1 antibody, Transforming growth factor-beta-signaling protein 1 antibody

UniProt: Q15797

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development