NAGPA antibody (AA 327-438) (HRP)

Catalog No. ABIN7160687

This Rabbit Polyclonal antibody specifically detects NAGPA in ELISA. It exhibits reactivity toward Human.

Quick Overview for NAGPA antibody (AA 327-438) (HRP) (ABIN7160687)

Target: NAGPA (N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAGPA antibody is conjugated to HRP

Application: ELISA

Product Details anti-NAGPA Antibody (HRP)

Binding Specificity: AA 327-438

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase protein (327-438AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NAGPA

Target: NAGPA (N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA))

Alternative Name: NAGPA

Background:

Background: Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N-acetylglucosaminyltransferases.

Aliases: Mannose 6-phosphate-uncovering enzyme antibody, N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase antibody, NAGPA antibody, NAGPA_HUMAN antibody, Phosphodiester alpha-GlcNAcase antibody

UniProt: Q9UK23