NLRP1 antibody (AA 589-655) (FITC)

Catalog No. ABIN7160823

The Rabbit Polyclonal anti-NLRP1 antibody has been validated for . It is suitable to detect NLRP1 in samples from Human.

Quick Overview for NLRP1 antibody (AA 589-655) (FITC) (ABIN7160823)

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP1 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-NLRP1 Antibody (FITC)

Binding Specificity: AA 589-655

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human NACHT, LRR and PYD domains-containing protein 10 protein (589-655AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NLRP1

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Alternative Name: NLRP1

Background:

Background: Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID. Displays anti-inflammatory activity. Plays a role in adaptive immunity through control of dendritic cell-mediated transport of antigen to the lymph nodes from peripheral sites. Required for immunity against C.albicans infection. Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection.

Aliases: CLR11.1 antibody, NACHT, leucine rich repeat and PYD containing 10 antibody, NACHT, LRR and PYD domains containing protein 10 antibody, NACHT, LRR and PYD domains-containing protein 10 antibody, NAL10_HUMAN antibody, NALP10 antibody, NLR family, pyrin domain containing 10 antibody, Nlrp10 antibody, NOD8 antibody, Nucleotide-binding oligomerization domain protein 8 antibody, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10 antibody, PAN5 antibody, PYNOD antibody

UniProt: Q86W26

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome