NDUFA13 antibody (AA 52-144)

Catalog No. ABIN7160892

The Rabbit Polyclonal anti-NDUFA13 antibody has been validated for WB, ELISA and IHC. It is suitable to detect NDUFA13 in samples from Human.

Quick Overview for NDUFA13 antibody (AA 52-144) (ABIN7160892)

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NDUFA13 Antibody

Binding Specificity: AA 52-144

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 protein (52-144AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: NDUFA13

Background:

Background: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.

Aliases: 2700054G14Rik antibody, AU022060 antibody, B16.6 antibody, CDA016 antibody, Cell death regulatory protein antibody, Cell death regulatory protein GRIM-19 antibody, CGI-39 antibody, CGI39 protein antibody, CI-B16.6 antibody, Complex I-B16.6 antibody, FLJ58045 antibody, FLJ59191 antibody, Gene associated with retinoic and IFN-induced mortality 19 protein antibody, Gene associated with retinoic and interferon-induced mortality 19 protein antibody, Gene associated with retinoic interferon induced mortality 19 protein antibody, GRIM-19 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antibody, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 antibody, NADH ubiquinone oxidoreductase B16.6 subunit antibody, NADH-ubiquinone oxidoreductase B16.6 subunit antibody, NDUAD_HUMAN antibody, NDUFA13 antibody, RGD1565358 antibody

UniProt: Q9P0J0

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling