NKIRAS2 antibody (AA 1-191) (Biotin)

Catalog No. ABIN7161535

Product Details anti-NKIRAS2 Antibody (Biotin)

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Binding Specificity: AA 1-191

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKIRAS2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human NF-kappa-B inhibitor-interacting Ras-like protein 2 protein (1-191AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NKIRAS2

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Alternative Name: NKIRAS2 (NKIRAS2 Products)

Synonyms: NKIRAS2 antibody, KBRAS2 antibody, kappaB-Ras2 antibody, zgc:92870 antibody, 2410003M04Rik antibody, 4930527H08Rik antibody, D630018G21Rik antibody, NFKB inhibitor interacting Ras like 2 antibody, NFKB inhibitor interacting Ras-like 2 antibody, NFKB inhibitor interacting Ras like 2 L homeolog antibody, NFKB inhibitor interacting Ras-like protein 2 antibody, NKIRAS2 antibody, Nkiras2 antibody, nkiras2 antibody, nkiras2.L antibody

Background:

Background: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).

Aliases: DKFZP434N1526 antibody, I kappa B interacting Ras like protein 2 antibody, I-kappa-B-interacting Ras-like protein 2 antibody, Kappa B Ras protein 2 antibody, Kappa B-Ras protein 2 antibody, KappaB Ras2 antibody, KappaB-Ras2 antibody, KBRAS 2 antibody, KBRAS2 antibody, KBRS2_HUMAN antibody, MGC74742 antibody, NF kappa B inhibitor interacting Ras like protein 2 antibody, NF-kappa-B inhibitor-interacting Ras-like protein 2 antibody, NFKB inhibitor interacting Ras like 2 antibody, NFKB inhibitor interacting Ras like protein 2 antibody, NKIRAS 2 antibody, NKIRAS2 antibody

UniProt: Q9NYR9