NFAM1 antibody (AA 186-270) (Biotin)

Catalog No. ABIN7161543

Product Details anti-NFAM1 Antibody (Biotin)

Target: NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))

Binding Specificity: AA 186-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFAM1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human NFAT activation molecule 1 protein (186-270AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NFAM1

Target: NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))

Alternative Name: NFAM1 (NFAM1 Products)

Synonyms: 4921501M20Rik antibody, Cnaip antibody, CNAIP antibody, bK126B4.4 antibody, RGD1308316 antibody, NFAT activating protein with ITAM motif 1 antibody, Nfat activating molecule with ITAM motif 1 antibody, NFAM1 antibody, Nfam1 antibody

Background:

Background: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

Aliases: NFAM1 antibody, CNAIPNFAT activation molecule 1 antibody, Calcineurin/NFAT-activating ITAM-containing protein antibody, NFAT-activating protein with ITAM motif 1 antibody

UniProt: Q8NET5