NFAM1 antibody (AA 186-270) (FITC)
Quick Overview for NFAM1 antibody (AA 186-270) (FITC) (ABIN7161544)
Target
See all NFAM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 186-270
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human NFAT activation molecule 1 protein (186-270AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
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Alternative Name
- NFAM1
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Background
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Background: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
Aliases: NFAM1 antibody, CNAIPNFAT activation molecule 1 antibody, Calcineurin/NFAT-activating ITAM-containing protein antibody, NFAT-activating protein with ITAM motif 1 antibody
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UniProt
- Q8NET5
Target
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